One of my possibly annoying habits is inserting pop-culture references into random conversation. I have a large store of song lyrics and movie quotes swimming around in the back of my head, and they have a tendency to pop out when they seem vaguely relevant. A lot of the time I don't even realise I'm doing it until too late.
This can be particularly annoying on IRC, where I am quite capable of spending hours doing nothing but interjecting the occasional line from a song into the conversation.
Paradoxically, when that meme was going around a few years ago where you had to answer a series of questions about yourself using only lyrics or quotes, I was unable to do it. I guess that has something to do with how much I suck at improvisation when I'm put on the spot. I can free-associate when the pressure's off, but sit me down and order me to think of a relevant quote for something specific, and my brain seizes up.
By far my favourite, and most common quote, however, has to be this (although I usually misquote it slightly):
I say we take off and nuke the entire site from orbit. That's the only way to be sure.
It's applicable to so many different situations.